On Dec. 31, 2015, the National IHR Focal Point (NFP) of the United States of America notified the Pan-American Health Organization (PAHO) and the World Health Organization (WHO) of the first laboratory-confirmed case of Zika virus infection in the Commonwealth of Puerto Rico, an unincorporated territory of the United States. The patient is a resident of Puerto Rico and had no travel history outside the island in the three months prior to the onset of illness. A blood sample obtained from the patient tested positive for Zika viral RNA by reverse transcription polymerase chain reaction (RT-PCR).
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