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Development and Virucidal Activity of a Novel Alcohol-Based Hand Disinfectant

Monday, February 22, 2016   (0 Comments)

Hand hygiene is important for the prevention of bacterial and viral transmission in the healthcare environment. The development of broad antiviral spectrum hand disinfectants with activity against enveloped and non-enveloped viruses is limited due to a small number of permissible active ingredients able to inactivate viruses. Ionidis et al. (2016) report on a new hand disinfectant that was developed based upon 69.39% w/w ethanol and 3.69% w/w 2-propanol. Different amounts of citric acid and urea were added in order to create a virucidal claim against poliovirus (PV), adenovirus type 5 (AdV) and polyomavirus SV40 (SV40) as non-enveloped test viruses in the presence of fetal calf serum (FCS) as soil load. The exposure time was fixed to 60 seconds.


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