Alexander Fleming’s discovery of penicillin in 1928 is one of the greatest medical advancements in history.1 The introduction of antibiotics meant that infectious diseases that were once deadly could now be cured. Since 1928, countless lives have been saved, and antibiotics have been recognized as miracle drugs. However, as antibiotic use has become more prevalent, so have antibiotic-resistant bacteria and adverse events associated with their use.2,3 In his 1945 Nobel Lecture, Fleming warned of the danger of overreliance on antibiotics and the threat of bacteria developing resistance.
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