| FAQ - Disinfection - 2013
What if anything can you tell me about accelerated hydrogen peroxide disinfectants. The company claims it has a 5 minute kill time for TB. Does having the claim that it is EPA registered help? Currently we use Product A and that has a 10 minute kill time for TB. Thanks
Ask OSAP does not review, evaluate, certify, recommend or endorse products. Ask OSAP also does not provide technical support for specific products. If you have further questions about procedures and specific products it is recommended that you consult with the manufacturer’s written instruction manual and/or contact the manufacturer of your product.
Practical Infection Control In Dentistry states as follows:
The history of hydrogen peroxide use as an antimicrobial agent spans almost 200 years, with periodic applications for various products as disinfectants, antiseptics, or chemical sterilants. Some early preparations were found to be unstable and yielded only low levels of the chemical. This observation was partially responsible for the decline of hydrogen peroxide as a antiseptic for wounds. Later formulations have attempted to correct previous problems with chemical stability and activity.
Hydrogen peroxide acts as an oxidant in tissues and microorganisms, yielding high concentrations of antimicrobial hydroxyl radicals. Accumulation of this anion is able to adversely affect multiple sites in bacterial cells, including membrane lipids, DNA, and other cell components. As a result, hydrogen peroxide is active against a wide range of microorganisms. It was marketed and used for many years as an antiseptic, where it served the dual purpose as an antimicrobial oxidant and a debriding agent for treating infection. Much of its clinical use in recent years has been as an effective chemical sterilant (6%), with an immersion time of 6 hours. Sporicidal activity can is attained at this high concentration with the extended immersion time. In recent years, accelerated and stabilized hydrogen peroxide formulations have been developed and found to be effective environmental surface cleaners and disinfectants. 1
Infection Control and Management of Hazardous Materials for the Dental Team states as follows:
Manufacturers of disinfectants must submit testing data on the antimicrobial activity and safety of their products to the EPA. If the data are consistent with the claims stated on the product labeling and other requirements are met, the EPA registers the product. The US Food and Drug Administration also must grant marketing clearance to liquid chemical sterilants/high-level disinfectants labeled for use on medical devices, such as heat-sensitive dental items. 2
The US Environmental Protection Agency (EPA) has information on its Website regarding selected EPA-registered disinfectants which can be accessed here:
It is recommended that if you have further product specific questions that you contact the manufacturer of the product directly.
1) Molinari JA and Harte JA. Practical Infection Control In Dentistry – Third Edition. Wolters Kluwer / Lippincott / Williams & Wilkins. Page 181.
2) Miller CH. Infection Control and Management of Hazardous Materials for the Dental Team, 5th edition. Elsevier/Mosby Publishers. Page 159.
3) US Environmental Protection Agency. Selected EPA-registered Disinfectants. http://www.epa.gov/oppad001/chemregindex.htm Accessed on May 17, 2013.